{"id":11203,"date":"2025-05-23T17:58:18","date_gmt":"2025-05-23T15:58:18","guid":{"rendered":"https:\/\/www.adacyte.com\/what-do-ulcerative-colitis-patients-prefer-in-their-treatments\/"},"modified":"2025-05-23T17:58:18","modified_gmt":"2025-05-23T15:58:18","slug":"what-do-ulcerative-colitis-patients-prefer-in-their-treatments","status":"publish","type":"post","link":"https:\/\/www.adacyte.com\/de\/what-do-ulcerative-colitis-patients-prefer-in-their-treatments\/","title":{"rendered":"What Do Ulcerative Colitis Patients Prefer in Their Treatments?"},"content":{"rendered":"<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>Over the past decades, therapeutic options for ulcerative colitis patients have expanded considerably, creating new challenges for both patients and physicians when deciding on treatment. A recent study conducted at Leiden University in the Netherlands investigated what priorities&nbsp; ulcerative colitis (UC) patients have when choosing a treatment and at what point they would consider surgery after failing multiple treatment options, with the understanding that the decision is based on the clinical judgment of the healthcare professional.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<h2 class=\"wp-block-heading\"><strong><strong>What was investigated in this study?<\/strong><\/strong><\/h2>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>The study included 172 adult patients with UC, who were asked to choose between different hypothetical treatment options based on several attributes:<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<ul class=\"wp-block-list\">\n<li>The route and site of administration (oral, subcutaneous injection, or intravenous infusion).<\/li>\n\n\n\n<li>The likelihood of short- and long-term symptom reduction (over eight weeks or one year).<\/li>\n\n\n\n<li>Risk of infections and other adverse effects.<\/li>\n<\/ul>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<h2 class=\"wp-block-heading\"><strong><strong><strong>Key findings: What matters most to patients?<\/strong><\/strong><\/strong><\/h2>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>Patients indicated that the most important feature when choosing a treatment was the <strong>reduction in symptoms after one year <\/strong>(27.7% importance). In second place, they mentioned the <strong>likelihood of infection <\/strong>(22.3%), and in third place, <strong>symptoms reduction in in the first eight weeks <\/strong>(19.5%).<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>In addition, it was found that:<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<ul class=\"wp-block-list\">\n<li>The route of administration is also an important factor, with preference for oral administration over subcutaneous or intravenous administration.<\/li>\n<\/ul>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<ul class=\"wp-block-list\">\n<li><strong>14.3 % of patients stated that they would not consider surgery,<\/strong> even if they failed eight medical treatments.<\/li>\n\n\n\n<li><strong>Only 9 patients would opt for surgery, <\/strong>without trying any medical therapy.<\/li>\n<\/ul>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>In summary, the study highlights that long-term symptom reduction is the most important factor for UC patients when selecting a treatment, above adverse effects or route of administration. In addition, patients with no prior experience with biologics or small molecules were more likely to value route of administration compared to those with experience with these treatments.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<h2 class=\"wp-block-heading\"><strong><strong><strong>Why is this study important?<\/strong><\/strong><\/strong><\/h2>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>These findings help clinicians understand what UC patients value most when choosing their treatment. Knowing that <strong>long-term symptom reduction is the top priority<\/strong> allows for the design of strategies that ensure individual preferences are taken into account to optimize treatment adherence and patient quality of life.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>In conclusion, this study highlights the importance of prioritizing treatments with high long-term effectiveness and lower risk of infections as well as oral treatments. By better understanding patients&#8216; preferences, clinicians can make decisions together with patients, ensuring a more appropriate and satisfactory treatment.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<h2 class=\"wp-block-heading\"><strong><strong><strong>Reference<\/strong><\/strong><\/strong><\/h2>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>1. Tessa Straatmijer , M. Elske van den Akker -van Marle , Cyriel Y. Ponsioen , Danielle van der Horst , Menne PM. Scherpenzeel , Marjolijn Duijvestein &amp; Andrea E. van der Meulen -de Jong (2024) Patient preferences in treatment options of ulcerative colitis: a discrete choice experiment , Scandinavian Journal of Gastroenterology , 59:3, 288-295, <a href=\"https:\/\/doi.org\/10.1080\/00365521.2023.2286191\">https:\/\/doi.org\/10.1080\/00365521.2023.2286191<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Over the past decades, therapeutic options for ulcerative colitis patients have expanded considerably, creating new challenges for both patients and physicians when deciding on treatment. A recent study conducted at Leiden University in the Netherlands investigated what priorities&nbsp; ulcerative colitis (UC) patients have when choosing a treatment and at what point they would consider surgery [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":10709,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[643],"tags":[],"class_list":["post-11203","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nachrichten"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>What Do Ulcerative Colitis Patients Prefer in Their Treatments? - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/de\/what-do-ulcerative-colitis-patients-prefer-in-their-treatments\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What Do Ulcerative Colitis Patients Prefer in Their Treatments? - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Over the past decades, therapeutic options for ulcerative colitis patients have expanded considerably, creating new challenges for both patients and physicians when deciding on treatment. 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